Pleural Mesothelioma
Pleural mesothelioma is the most common form of mesothelioma. Pleural (pleura is the thin lining or coverings of lungs) mesothelioma generally occurs to individuals exposed to high level of asbestos. Exposure to high level of asbestos for 10 or more years is generally required for pleural mesothelioma to develop. Pleural mesothelioma may occur, like other forms of mesothelioma, even decades (sometimes as late as 30 years after last exposure to asbestos) after last exposure to asbestos.
Pleural mesothelioma may start as simple pleural disease such as calcification of pleura or thickening of pleural lining and it is not uncommon to diagnose them as pleural calcification, pleural thickening or pleural plaques. As these pleural diseases are not fatal disease, they may be ignored and later on these pleural diseases may lead to development of pleural mesothelioma. Pleural diseases may not be fatal but they impair normal functioning of lungs and should be addressed appropriately. If a patient with pleural disease gives a history of asbestos exposure even only for a brief period the diagnosis of pleural mesothelioma should be considered.Categories: Mesothelioma Tags:
What can affect life Expectancy of Mesothelioma Patients?
There are various factors that can affect the prognosis and life expectancy (survival) of mesothelioma patients. Some of the factors have greater affect on the survival of mesothelioma patients than others. The common factors that influence survival and life expectancy of a mesothelioma patiets are:
- Type of mesothelioma: Generally three types of mesothelioma are common and they are pleural, peritoneal (lining of abdomen) and pericardial (covering of heart is known as pericardium) mesothelioma. There can also be other uncommon types of mesothelioma like testicular mesothelioma. Pleural mesothelioma is the commonest type which affects the pleura or the lining or the coverings of lungs. Generally patients with pleural mesothelioma lives longer, because it is the commonest form of mesothelioma and most of the research and treatment studies are done on pleural mesothelioma in compare to other less common types.
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How is the Prognosis of Mesothelioma?
In the United States more than 2,000 new cases of mesothelioma are diagnosed every year and most of the cases are due to exposure to asbestos due to presence of asbestos in the work place of some indirect exposure to asbestos. It is only natural for the patient to know about the possible prognosis of the disease he/she has developed. The disease may be mild simple viral fever or a cancer like mesothelioma. Even it becomes a duty of the doctor diagnosing the mesothelioma or treating the disease to discuss the possible prognosis of mesothelioma or any other disease and also the probable influence mesothelioma will have on the normal functioning of the patient of mesothelioma.
The factors which may influence the prognosis of mesothelioma are many. The most important factor that influence the prognosis of mesothelioma is detection time, the earlier it is diagnosed the better is the prognosis; unfortunately most of the mesotheliomas are diagnosed when they are in late stage.Categories: Mesothelioma Tags:
New Possibilities of Mesothelioma Treatment
Mesothelioma is a relatively rare cancer, but the outcome of the cancer is not favorable. The treatment options (generally surgical, radiotherapy and chemotherapy options are available for treatment of mesothelioma) that are available at present are not satisfactory.
At NCI (National Cancer Institute) there are certain modalities of treatment procedures are being studied. Several clinical trials (research studies involving people with mesothelioma and normal people without mesothelioma) are being done to find out the best available treatment option for mesothelioma. The clinical trials are for finding out the best ways to use among presently available treatment options and also to try to find out new treatment modalities.
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How Mesothelioma is Treated
Treatment of mesothelioma depends on many factors. These factors are mainly of patient related, like the stage of mesothelioma, the location of the mesothelioma cancer, general health status of the patient and also the age of the patient. In general like any other cancer mesothelioma has three options of treatment, which may be used alone or in combination one two or more options together. The standard treatment options of mesothelioma are surgery, radiotherapy and chemotherapy.
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How Mesothelioma is diagnosed?
Diagnosis of mesothelioma may pose a problem due to the similarity of the symptoms and signs with many other medical conditions, especially those of respiratory diseases. But sometimes the diagnosis can be predicted based on careful assessment of clinical and radiological findings (if accurate diagnosis is not possible, a good guess can be made).
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Risk Factors of Mesothelioma
The incidence of mesothelioma: Mesothelioma is a relatively rare cancer, although there is an increase incidence of mesothelioma in the last 20 years, but still a rare disease. Approximately 2,000 new cases of mesothelioma are diagnosed every year in the United States. Mesothelioma occurs more commonly in men than in women. The risk of mesothelioma increases with age, but this disease can appear in either at any age, as well as 30-40 years of exposure to risk factors.
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Who are at Risk of Developing Mesothelioma?
The only major risk factor of development of Mesothelioma cancer is the exposure to asbestos, which may be chronic occupational exposure or accidental chronic exposure (e.g. living in houses made of asbestos roof shingles). Since 19th century asbestos is mined and used commercially till date. The use of asbestos was greater during II World War. The use of asbestos was much more before discovery of asbestos as the only major cause of mesothelioma.
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Symptoms and Signs of Mesothelioma
Symptoms and Signs of Mesothelioma can vary according to the location of mesothelioma like mesothelioma of pleura (Pleural mesothelioma) can cause shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space (known as pleural effusion). Pleural mesothelioma can also cause weight loss, cachexia (extreme weight loss seen in cancer patients) pain in the chest wall, fatigue, wheezing, hoarseness, hemoptysis (blood in the sputum). In severe cases of Pleural mesothelioma there may be collapse of lungs, pneumo-thorax etc.
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What is Mesothelioma?
Mesothelioma is a primary malignant (cancerous) tumor of mesothelial cells and the commonest site of mesothelioma is the lungs or pleura. But sometimes mesothelioma may also occur though rarely in peritoneum (it is the lining of abdominal cavity), pericardium (outer covering of the heart) or tunica vaginalis. Mesothelial cells line pleural cavity of the lungs, so it is common in the lungs. Pleura is the covering of the lungs. Mesothelial cells also line other body’s internal organs (but mesothelioma occurs rarely).
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